Research

Pulmonary and critical care medicine fellows participate in ongoing mentored research projects and become proficient in the critical assessment of the medical literature pertinent to pulmonology and critical care medicine. To advance fellow’s professional development and research experience, dedicated research faculty members provide additional support and expertise. Current faculty research interests include evaluation of interstitial lung disease, COPD management, reduced morbidity of the critically ill patient, venous thromboembolism, ventilator management and liberation, complicated pleural space management, lung transplantation and ECMO, and diagnostic modalities in lung cancer. Faculty research studies have included monoclonal antibody therapy in COVID-19, fecal microbial transplantation protocol implementation, outcomes for ECMO patients and lung transplantation, reduction of mountain sickness in COPD patients, fatigue in critically ill family members, caregiver burden evaluation for chronic pulmonary conditions, and spirometry evaluations of active duty personnel.

Each fellow is expected to have at least one submission for peer‐reviewed publication during the three-year fellowship. Other scholarly activities include case reports and clinical case series, book chapters, as well as presentations at regional and national meetings. Fellows are provided protected time for pursuit of meaningful research and advancement of best practices. Additional training and statistical support is also available through the Research Institute at St. Luke’s University Hospital in Bethlehem, PA.

Select Publications

Brodsky A, Dotan Y, Samri M, Schwartz AR, Oliven A. Differential effects of respiratory and electrical stimulation-induced dilator muscle contraction on mechanical properties of the pharynx in the pig. J Appl Physiol. 2016. doi: 10.1152/japplphysiol.00783.2015

Cipriano A, Roscher C, Carmona A, Rowbotham J, Wojda TR, Guglielmello G, Stawicki SP. Reducing telemetry use while improving patient outcomes: University health network experience with the implementation of oximetry-based monitoring system. Int J Academic Med. 2018 May-Aug;4(2):96-105

Corwin D, Shah NG, Ramarathnam A, et al. Hypothermia and Trpv4 channel inhibition mitigates thrombin-induced endothelial permeability. Am J Respir Crit Care Med. 2016;193:A1358.

Derzec O, Croitoru, S, Dotan Y, Schiff E, Oliven A. Integrating D-dimer levels in revised Wells Score to improve the clinical prediction of pulmonary embolism. Jacobs J Pulmonol. 2016.

Dotan Y, Marchetti N, Criner GJ. Re-expansion pulmonary edema as a complication of endobronchial valve placement. J Bronchology Interv Pulmonol. 2017. doi: 10.1097/LBR.0000000000000391

Dotan Y, Pillar G, Schwartz AR, Oliven A. Asynchrony of lingual muscle recruitment during sleep in obstructive sleep apnea. J Appl Physiol. 2015.

Duarte Chavez R, Wojda TR, Zanders TB, Geme B, Fioravanti G, Stawicki SP. Early results of fecal microbial transplantation protocol implementation at a community based university hospital. J Glob Infect Dis. 2017. doi: 10.4103/jgid.jgid_145_17

Kim V, Guo J, Guglielmello G, et al. Differences in core peel emphysema phenotypes between gender and race in the COPDgene study. Am J of Res and Critical Care Medicine. 2015;191:1-2.

Kwon HP, Zanders TB, Regn DD, Burkett SE, et al. Comparison of virtual bronchoscopy to fiber-optic bronchoscopy for assessment of inhalation injury severity. Burns. 2014 Nov;40(7):1308-15. doi: 10.1016/j.burns.2014.06.007

Morris MJ, Lucero PF, Zanders TB, Zacher LL. Diagnosis and management of chronic lung disease in deployed military personnel. Ther Adv Respir Dis. 2013. doi: 10.1177/1753465813481022

Punjabi CD, Lai YK, Numeir M, Murali G. Don’t waste your breath. Ann Am Thorac Soc. 2014;(11)5: pp. 844-847. doi: 10.1513/AnnalsATS.201402-058CC

Ramana CV, DeBerge MP, Kumar A, Alia CS, Durbin JE, Enelow RI. Inflammatory impact of IFN-Interferon Gamma in CD8+ T cell-mediated lung injury is mediated by both Stat1-dependent and -independent pathways. Am J Physiol Lung Cell Mol Physiol. 2015 April;308(7):L650-7. doi: 10.1152/ajplung.00360.2014

Oliven R, Cohen G, Dotan Y, Somri M, Schwartz AR, Oliven A. Alteration in upper airway dilator muscle co-activation during sleep: comparison of patients with OSA and healthy subjects. J Appl Physiol. 2017. doi: 10.1152/japplphysiol.01067

Slack D, Corwin DS, Shah NG, et al., Terrin ML, Hasday JD. Pilot feasibility study of therapeutic hypothermia for moderate to severe acute respiratory distress syndrome. Crit Care Med. 2017 Jul; 45(7):1152-9. doi: 10.1097/CCM.0000000000002338

Slack D, Corwin DS, Buchner J, et al. Fever is common in patients with severe ARDS receiving neuromuscular blocking agents and associated with lack of improvement in oxygenation. Am J Respir Crit Care Med. 2016;193:A1851.

Verceles AC, Corwin DS, Afshar M, et al. Half of the family members of critically ill patients experience excessive daytime sleepiness. Intensive Care Med. 2014 Aug;40(8):1124-31. doi: 10.1007/s00134-014-3347-z